Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In Humans
نویسندگان
چکیده
منابع مشابه
Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans.
Insulin resistance plays an important role in the pathophysiology of diabetes and is associated with obesity and other cardiovascular risk factors. The "gold standard" glucose clamp and minimal model analysis are two established methods for determining insulin sensitivity in vivo, but neither is easily implemented in large studies. Thus, it is of interest to develop a simple, accurate method fo...
متن کاملHomeostasis model assessment is more reliable than the fasting glucose/insulin ratio and quantitative insulin sensitivity check index for assessing insulin resistance among obese children and adolescents.
OBJECTIVE Simple fasting methods to measure insulin resistance, such as the homeostasis model assessment (HOMA), fasting glucose/insulin ratio (FGIR), and quantitative insulin sensitivity check index (QUICKI) methods, have been widely promoted for adult studies but have not been evaluated formally among children and adolescents. The aim of this study was to compare the HOMA, FGIR, and QUICKI me...
متن کاملMethods for assessing insulin sensitivity in man.
13. Chiasson, J-L. & Cherrington, A. D. (1983) in Glucagon I , (Lefebvre, P. ed.), pp. 361-382, Springer-Verlag, Berlin 14. Frizzell, R. T., Hendrick, G . K., Biggers, D. W., Lacy, D. B., Donahue, D. P., Green, D. R., Carr, R. K., Williams, P. E., Stevenson, R. W. & Cherrington, A. D. (1987) Gluconeogenesis plays the major role in sustaining glucose production during hypoglycemia in response to...
متن کاملComparison of the homeostasis model assessment and quantitative insulin sensitivity check index with data from forearm metabolic studies for the in vivo assessment of insulin sensitivity.
The present study was designed to compare the homeostasis model assessment (HOMA) and quantitative insulin sensitivity check index (QUICKI) with data from forearm metabolic studies of healthy individuals and of subjects in various pathological states. Fifty-five healthy individuals and 112 patients in various pathological states, including type 2 diabetes mellitus, essential hypertension and ot...
متن کاملQuantitative estimation of insulin sensitivity.
We have evaluated the feasibility of using a mathematical model of glucose disappearance to estimate insulin sensitivity. Glucose was injected into conscious dogs at 100, 200, or 300 mg/kg. The measured time course of insulin was regarded as the "input," and the falling glucose concentration as the "output" of the physiological system storing and using glucose. Seven mathematical models of gluc...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2000
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.85.7.6661